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What Is Type 3 Diabetes? Mayo Clinic and Dr. Martin

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Brain and blood sugar

What Is Type 3 Diabetes? Mayo Clinic and Dr. Martin

Type 3 diabetes is a name for Alzheimer's disease seen as diabetes of the brain: brain cells that can no longer use insulin properly. Mayo Clinic has used the term, and its researchers describe it as a research term rather than an official diagnosis. Dr. Martin has taught it since 2005, and he puts insulin resistance at the center of it.

Key takeaways

  • Type 3 diabetes means Alzheimer's as diabetes of the brain.
  • Mayo Clinic calls it a research term, not a diagnosis.
  • Dr. Martin says insulin resistance is the biggest problem behind it.
  • His prevention starts in the kitchen: cut sugar and crappy carbs.
A woman in her sixties sitting at her kitchen table with her head resting on her hand
Losing the memory is the fear Dr. Martin hears most from people as they get older. Episode 1232.

What is type 3 diabetes?

Type 1 and type 2 diabetes are about blood sugar in the body. Type 3 diabetes is the idea that Alzheimer's is the same problem in the brain. Dr. Martin dates it to 2005, when he was hosting a radio show and read the research as it came out.

In 2005, they called Alzheimer's. It was named type three diabetes because it was diabetes of the brain.

Dr. Martin, The Doctor Is In, Episode 1232

It became a big topic on that show for weeks. He kept waiting for it to hit the news, and in his telling it never really caught on with doctors. He has been teaching it ever since.

What Mayo Clinic says about type 3 diabetes

This is why so many people search for Mayo Clinic and type 3 diabetes together. When Dr. Martin read that Mayo was using the term, he was delighted.

Mayo Clinic is now starting to call Alzheimer's type three diabetes.

Dr. Martin, The Doctor Is In, Episode 1306

To be precise about it, Mayo Clinic's own pages on the subject are research news, not a diagnosis page. In a 2018 Mayo Clinic research post, one of its researchers described it as more of a research term than a medical term, and your doctor will not write it on a chart. What the term points to, brain cells that stop responding to insulin, is the part Dr. Martin cares about.

Is Alzheimer's a form of diabetes?

In Dr. Martin's view, yes, at the level of the brain. His picture is a brain surrounded by fuel it cannot use.

The brain is swimming in fuel, but the wrong type, okay? There's fuel up there, but it's glucose and the brain is swimming in it and it can't use it.

Dr. Martin, The Doctor Is In, Episode 1306

He compares it to swimming in the Atlantic while you are dehydrated. The water is all around you and you cannot drink it. For years the focus in Alzheimer's has been amyloid plaque. He accepts plaque is part of the picture, but he does not think it is where the problem starts.

How insulin resistance affects the brain

Insulin's job is to take sugar out of the blood and put it away. Eat sugar and crappy carbs long enough and your cells stop answering it. That is insulin resistance, and he calls it the biggest problem behind Alzheimer's.

We know that in Alzheimer's, 50%, that insulin has trouble crossing the blood brain barrier when you have insulin resistance. Now, insulin can't go get the sugar.

Dr. Martin, The Doctor Is In, Episode 1232

So the sugar sits there. He calls insulin resistance one of the biggest causes of inflammation in the brain, and inflammation over a long period of time is what he links to the damage. More on how he spots it early: insulin resistance in women over 60.

Can you have type 3 diabetes without diabetes?

This is the part that surprises people. Dr. Martin says your blood sugar numbers can look fine and your brain can still be in trouble.

That even though you weren't a diabetic, I mean officially your brain was a diabetic, and that's Alzheimer's.

Dr. Martin, The Doctor Is In, Episode 1166

He says the same thing about how you look. Being slim is no guarantee, because fat can be stored around the organs and in the liver where you cannot see it.

Your brain becomes diabetic before the rest of you becomes diabetic. Hey, you can be skinny as the rake.

Dr. Martin, The Doctor Is In, Episode 1043

You might not have diabetes anywhere else that you know of, but you've got diabetes of the brain. You've got insulin resistance of the brain.

Dr. Martin, The Doctor Is In, Episode 1516

If you already have type 2 diabetes or prediabetes, he sees it as the same story moving through the body. See can you get diabetes after 60.

Type 3 diabetes and the five types of dementia

Alzheimer's is one form of dementia. In this episode Dr. Martin drew the five types on a board, with his own rough breakdown:

  • Alzheimer's, about 50% of cases. The brain shrinks. This is the one he calls type 3 diabetes.
  • Vascular dementia, about 20%, from blood supply, often after a stroke or small vessel disease.
  • Lewy body dementia, about 15%, abnormal cells in the brain. He sees it and Alzheimer's as two sides of one coin.
  • Parkinson's dementia, about 5%.
  • Frontal lobe dementia, about 5%, abnormal proteins in the brain.

50% of the cases of dementia are Alzheimer's.

Dr. Martin, The Doctor Is In, Episode 1232

That is why he talks about blood sugar and the brain almost every day. Surveys of older people, he says, put losing their memory above even dying as the biggest fear.

What Dr. Martin says to do about it

He is careful not to promise anything.

There's no guarantee of that. But you do everything you can.

Dr. Martin, The Doctor Is In, Episode 1232

Everything you can, in his book, starts with food.

We wanna do prevention of Alzheimer's. Start in the kitchen if nothing else.

Dr. Martin, The Doctor Is In, Episode 961

Get rid of sugar and the sweet tooth, and lay off the crappy carbs. Then the rest of his list from this episode:

  • Sun. Vitamin D for the brain's battery packs, the mitochondria.
  • Steak. Eggs, meat and cheese for B12, cholesterol and fat, which he says the brain depends on.
  • Steel. Muscle, especially the legs, because muscle helps with insulin.
  • Sleep. Your brain clears out its garbage while you sleep. A 15 to 20 minute nap counts.
  • Also on his list: DHA, coffee, probiotics and pine bark.

Whenever you do leg exercises, think of your brain.

Dr. Martin, The Doctor Is In, Episode 1232

If brain fog is what has you worried, start with brain fog in women over 60. And if you have a diagnosis or take medication for your blood sugar, make changes with your own doctor.

Common questions

What is type 3 diabetes?

It is a name for Alzheimer's disease seen as diabetes of the brain, where brain cells cannot use insulin properly. Dr. Martin dates the term to research in 2005.

Does Mayo Clinic recognize type 3 diabetes?

Mayo Clinic has used the term in its research news, and a Mayo researcher has called it a research term rather than a medical diagnosis.

Is Alzheimer's type 3 diabetes?

Dr. Martin says yes. He describes the Alzheimer's brain as swimming in glucose it cannot use because of insulin resistance.

Can you have type 3 diabetes without having diabetes?

In his view, yes. He says your brain can become diabetic before the rest of you does, even if you are slim.

How do you lower your risk of type 3 diabetes?

Dr. Martin starts in the kitchen: cut sugar and crappy carbs. Then sun, steak, steel and sleep.

Keeping an eye on your blood sugar?

For Dr. Martin, the plate comes first: less sugar, more real food. Blood Sugar Support Formula is the clinic's blend of seven botanicals and nutrients, made to support healthy blood sugar levels as part of that.

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Dr. Martin
About the author

Dr. Martin

Host of The Doctor Is In. Formulated in clinic. Used in clinic since 1911.